Publications and health information

The Breastfeeding and HIV International Transmission Study (BHITS) Group. Late postnatal transmission of HIV-1 in breastfed children: an individual patient data meta-analysis. Journal of Infectious Diseases. 2004;189:2154-2166.

The Breastfeeding and HIV International Transmission Study Group. Mortality among HIV-1 infected women according to children’s feeding modality: an individual patient data meta-analysis. Journal of Acquired Immune Deficiency Syndrome. 2005;39:430-438.

Butto S, Fiorelli V, Tripiciano A, Ruiz-Alvarez MJ, Scoglio A, Ensoli F, Ciccozzi M, Collacchi B, Sabbatucci M, Cafaro A, Guzman CA, Borsetti A, Caputo A, Vardas E, Colvin M, Lukwiya M, Rezza G, Ensoli B; Tat Multicentric Study Group. Sequence conservation and antibody cross-recognition of clade B human immunodeficiency virus (HIV) type 1 Tat protein in HIV-1-infected Italians, Ugandans, and South Africans. Journal of Infectious Diseases. 2003 Oct 15;188(8):1171-80.

Buve A, Kalibala S, McIntyre J. Stronger health systems for more effective HIV/AIDS prevention and care. International Journal of Health Planning and Management. 2003 Oct-Dec;18 Suppl 1:S41-51.

Chersich M, Gray G. Progress and emerging challenges in preventing mother-to-child transmission. Current Infectious Disease Reports. 2005 Sep;7(5):393- 400. Review.

Coovadia H, Fowler MG, Lockman S, McIntyre J. Roundtable. Revisiting the role of single-dose nevirapine for preventing perinatal HIV transmission. AIDS Clinical Care. 2005 Jul;17(7):61-4.

Coplan PM, Gupta SB, Dubey SA, Pitisuttithum P, Nikas A, Mbewe B, Vardas E, Schechter M, Kallas EG, Freed DC, Fu TM, Mast CT, Puthavathana P, Kublin J, Brown Collins K, Chisi J, Pendame R, Thaler SJ, Gray G, McIntyre J, Straus WL, Condra JH, Mehrotra DV, Guess HA, Emini EA, Shiver JW. Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents. Journal of Infectious Diseases. 2005 May 1;191(9):1427-1434.

Dabis F, Balestre E, Braitstein P, Miotti P, Brinkhof WG, Schneider M, Schechter M, Laurent C, Boulle A, Kabugo C, Capkun G, Seyler C, McIntyre J, Sprinz E, Bangsberg D, Van der Borght S, Egger M; The Antiviral Therpapy in Lower Income Countries (ART-LINC) Study Group. Cohort profile: Antiretroviral therapy in lower income countries (ART-LINC): international collaboration of treatment cohorts. International Journal of Epidemiology. 2005 Oct;34(5):979-86.


De Bruyn G. Diarrhoea in adults (acute). Clin Evid. 2005 Jun;(13):896-916. Review. De Bruyn G, Hudgens MG, Sullivan PS, Duerr A. Participant retention in clinical trials of candidate HIV vaccines. Journal of Acquired Immune Deficiency Syndrome. 2005 Aug 1;39(4):499-501.

De Bruyn G, Vargas-Cortez M, Warren T, Tyring SK, Fife KH, Lalezari J, Brady RC, Shahmanesh M, Kinghorn G, Beutner KR, Patel R, Drehobl MA, Horner P, Kurtz TO, McDermott S, Wald A, Corey L. A Randomized controlled trial of a replication defective (gH deletion) herpes simplex virus vaccine for the treatment of recurrent genital herpes among immunocompetent subjects. Vaccine. 2005 Sep 21; In press, online publication Sep 2, 2005.

Dinat N, Russell A. Palliative care - a clinical approach for adults with HIV/AIDS. South African Journal of HIV Medicine. August 2003. [Article not available online].

Dunkle KL, Jewkes RK, Brown HC, Gray GE, McIntryre JA, Harlow SD. Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa. The Lancet. 2004 May 1; 363(9419):1415-1421.

Dunkle KL, Jewkes RK, Brown HC, Gray GE, McIntyre JA, Harlow SD. Transactional sex among women in Soweto, South Africa: prevalence, risk factors and association with HIV infection. Social Science & Medicine. 2004 Oct; 59(8):1581-1592.


Dunkle KL, Jewkes RK, Brown HC, Yoshihama M, Gray GE, McIntyre JA, Harlow SD. Prevalence and patterns of gender-based violence and revictimization among women attending antenatal clinics in Soweto, South Africa. American Journal of Epidemiology. 2004 Aug 1; 160(3):230- 239.

Fanales-Belasio E, Cafaro A, Cara A, Negri DRM, Fiorelli V, Butto S, Moretti S, Maggiorella MT, Sericola L, Scoglio A, Borsetti A, Ridolfi B, Bona R, Ten Haarft P, Macchia I, Leone P, Pavone-Cossut MR, Nappi F, Vardas E, Magnani M, Laguardia E, Caputo A, Titti F, Ensoli B. HIV-1 Tat based Vaccines: From basic science to clinical trials. DNA and Cell Biology. 2003, 21(9): 599-610.


Finlay A. Shaping the conflict: Factors influencing the representation of conflict around HIV/AIDS policy in the SA press. Communicare. 2004 Dec;23 (2).

Gray GE. Conducting HIV vaccine trials – Challenges for South Africa. S Afr J HIV Medicine, May 2003, 36-38. Hunt GM, Papathanasopoulos MA, Gray GE, Tiemessen CT. Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates. Virus Genes. 2003 Jan; 26(1):49-56.

Gray G, Gazzard B, Young B, Ho DD. Charting a successful course in antiretroviral treatment. Business Briefing: Long-Term Healthcare 2004. 25-27. Review. [Article not available online].

Gray CM, Williamson C, Bredell H, Puren A, Xia X, Filter R, Zijenah L, Cao H, Morris L, Vardas E, Colvin M, Gray G, McIntyre J, Musonda R, Allen S, Katzenstein D, Mbizo M, Kuwenda N, Taha T, Karim SA, Flores J, Sheppard HW. Viral Dynamics and CD4 T cell counts in subtype C human immunodeficiency virus type 1-infected individuals from southern Africa. AIDS Research and Human Retroviruses. 2005, Apr 21 (4) 285-91.

Gray GE, Urban M, Chersich MF, Bolton C, van Niekerk R, Violari A, Stevens W, McIntyre JA for the PEP Study Group. A randomized trial of two post-exposure prophylaxis regimens to reduce mother-to-child HIV-1 transmission in infants of untreated mothers. AIDS. 2005 Aug 12, 19:1289-1297.

Jaspan HB, Gray GE, Robinson AK, Coovadia HM, Bekker LG. Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa. South African Medical Journal. Sep; 95(9):685-7.

Johnson JA, Li JF, Morris L, Martinson N, Gray G, McIntyre J, Heneine W. Emergence of drug-resistant HIV-1 after intrapartum adminstration of single-dose nevirapine is substantially underestimated. Journal of Infectious Disease. 2005 Jul 1;192(1):16-23.

Leroy V, Sakarovitch C, Cortina-Borja M, McIntyre J, Coovadia H, Dabis F, Newell ML, Saba J, Gray G, Ndugwa Ch, Kilewo Ch, Massawe A, Kituuka P, Okong P, Grulich A, von Briesen H, Goudsmit J, Biberfeld G, Haverkamp G, Weverling GJ, Lange JM; Ghent Group on HIV in Women and Children. Is there a difference in the efficacy of peripartum antiretroviral regimens in reducing mother-to-child transmission of HIV in Africa? AIDS; 2005 Nov 4; 19(16):1865-75.

Madhi SA, Zar HJ, Saloojee H, Gray GE. Co-trimoxazole prophylaxis in African children with HIV-1. The Lancet. 2005 Feb 26;365(9461):749-50. Letter.

Masemola AM, Mashishi TN, Khoury G, Bredell H, Paximadis M, Mathebula T, Barkhan D, Puren A, Vardas E, Colvin M, Zijenah L, Katzenstein D, Musonda R, Allen S, Kumwenda N, Taha T, Gray G, McIntyre J, Karim SA, Sheppard HW, Gray CM; HIVNET 028 Study Team. Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa. Journal of Immunology. 2004 Oct 1;173(7):4607-17.

Masemola A, Mashishi T, Khoury G, Mohube P, Mokgotho P, Vardas E, Colvin M, Zijenah L, Katzenstein D, Musonda R, Allen S, Kumwenda N, Taha T, Gray G, McIntyre J, Karim SA, Sheppard HW, Gray CM of the HIVNET 028 Study Team. Hierarchical targeting of subtype C human immunodeficiency virus type 1 proteins by CD8+ T cells: correlation with viral load. Journal of Virology. 2004 April; 78(7):3233-3243.

Martinson, N., Morris, L., Gray, G, McIntyre, J. Prevention of mother-to-child transmission. A report-back from the XV International AIDS Conference, Bangkok, 11 – 16 July 2004. South African Journal of HIV Medicine. 2004 August: 17 – 21. Review.

McClure CA, Gray G, Rybczyk GK, Wright PF. Challenges to conducting HIV preventative vaccine trials with adolescents. Journal of Acquired Immune Deficiency Syndrome. 2004 Jun 1;36(2):726-733. Review.


McIntyre JA. Mothers infected with HIV. British Medical Bulletin. 2003;67:127-35. Review.


McIntyre J. Maternal health and HIV. Reproductive Health Matters. 2005 May;13(25):129-35.


McIntyre J. Preventing mother-to-child transmission of HIV: successes and challenges. BJOG: An International Journal of Obstetrics & Gynaecology. 2005 Sep;112(9):1196-203. Review.


McIntyre JA. Sex, pregnancy, hormones, and HIV. The Lancet. 2005 Oct 1;366(9492):1141-2.


McIntyre J. Prevention of mother-to-child transmission of HIV: treatment options. Expert Review of Anti-Infective Therapy. 2005 Dec;3(6):971-80.


Menu E, Scarlatti G, Barre-Sinoussi F, Gray G, Bollinger B, Ioannides JPA, Miotti P, Osborne C and the participants of the workshop. Mother-to-Child Transmission of HIV: developing integration of health care programmes with clinical, social and basic research studies. Report of the international workshop held at Chobe Marina Lodge, Kasane, Botswana, 21-25 January 2003. Acta Pediatrica. 92:1343 – 1348. Review.


Moodley D, Moodley J, Coovadia H, Gray G, McIntyre J, Hofmyer J, Nikodem C, Hall D, Gigliotti M, Robinson P, Boshoff L, and Sullivan JL; South African Intrapartum Nevirapine Trial (SAINT) Investigators. A multicentre randomised controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1. Journal of Infectious Disease. 2003 Mar 1; 187(5):725-735.


Morris L, Pillay C, Chezzi C, Lupondwana P, Ntsala M, Levin L, Venter F, Martinson N, Gray G, McIntyre J. Low frequency of the V106M mutation among HIV-1 subtype C-infected pregnant women exposed to nevirapine. AIDS. 2003 Jul 25;17(11):1698-1700.


Nachega J, Coetzee J, Adendorff T, Msandiwa R, Gray GE, McIntyre JA, Chaisson RE. Tuberculosis case finding in a mother-to-child transmission prevention programme in Soweto, South Africa. AIDS. 2003 Jun 13; 17(9): 1398 – 1400.


Naeem-Sheik A, Gray G. HIV disclosure in children. South African Journal of HIV Medicine. Nov 2005; p46-48.


Nwanegbo E, Vardas E, Gao W, Whittle H, Sun H, Robbins PD, Gambotto A. Prevalence of neutralizing antibodies to adenoviral serotypes 5 and 35 in the populations of Gambia, South Africa, and the United States. Clinical and Diagnostic Lab Immunology. 2004 Mar;11(2):351-7.


Rodriguez-French A, Boghossian J, Gray GE, Nadler JP, Quinones AR, Sepulveda GE, Millard JM, Wannamaker PG. The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy- naive HIV-1-infected patients. Journal of Acquired Immune Deficiency Syndrome. 2004 Jan 1;35(1):22-32.


Rollins N, Meda N, Becquet R, Coutsoudis A, Humphrey J, Jeffrey B, Kanshana S, Kuhn L, Leroy V, Mbori-Ngacha D, McIntyre J, Newell ML; Ghent IAS Working Group on HIV in Women and Children. Preventing postnatal transmission of HIV-1 through breast-feeding: modifying infant feeding practices. Journal of Acquired Immune Deficiency Syndrome. 2004 Feb 1;35(2):188-95. Review.


Rose P, Violari A, Bolton C, Gray GE. Feasibility and acceptability of postpartum voluntary counselling and testing (PPVCT) in a large tertiary hospital in the South African setting. South African Journal of HIV Medicine. June 2005: (19):8-10. Review.


Saez-Llorens X, Violari A, Deetz CO, Rode RA, Gomez P, Handelsman E, Pelton S, Ramilo O, Cahn P, Chadwick E, Allen U, Arpadi S, Castrejon MM, Heuser RS, Kempf DJ, Bertz RJ, Hsu AF, Bernstein B, Renz CL Sun E. Forty-eight-week evaluation of lopinavir / ritonavir, a new protease inhibitor, in human immunodeficiency virus-infected children. Pediatric Infectious Disease Journal. 2003 Mar; 22(3):216-24.


Shalekoff S, Gray GE, Tiemessen CT. Age-related changes in expression of CXCR4 and CCR5 on peripheral blood leukocytes from uninfected infants born to human immunodeficiency virus type 1-infected mothers. Clinical and Diagnostic Lab Immunology. 2004 Jan;11(1):229- 34.


Swartz L, Bhana A, Gray G, Kafaar Z, et al. Social and behavioural aspects of child and adolescent participation in HIV vaccine trials. Journal of International Association of Physicians in AIDS Care. 4(4):89-92.


Vardas E, Butto S, Glashoff R, Malnati MS, Poli G, Clerici M. Preparing for phase II/III HIV vaccine trials in Africa. Microbes and Infection. 2005 Nov;7(14):1436-44.


Williamson C, Morris L, Maughan M, Ping Li-Hua, Dryga SA, Thomas R, Reap E, Cilliers T, Van Harmelen J, Pascual A, Ramjee G, Gray G, Johnston R, Karim SA, Swanstrom R. Characterization and selection of HIV-1 subtype C isolates for use in vaccine development. AIDS Research and Human Retroviruses. 2003 Feb;19(2):133-44.


Wilson CM, Gray G, Read JS, Mwatha A, Lala S, Johnson S, Violari A, Sibiya PM, Fleming TR, Koonce A, Vermund SH, McIntyre J. Tolerance and safety of different concentrations of chlorhexidine for peripartum vaginal and infant washes: HIVNET 025. Journal of Acquired Immune Deficiency Syndrome. 2004 Feb 1;35(2):138-43.